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QUANTIFOIL® with circular holes

QUANTIFOIL® with circular holes is mainly used in cryo-EM. The roundness of the holes is advantageous with respect to the formation of an ice layer of constant thickness.

The QUANTIFOIL® types with small holes (e.g. 1.2 µm) were designed for magnifications around and higher 50.000x. At magnifications between 30.000x and 40.000x we recommend the QUANTIFOIL® types with 2 µm holes. Larger holes (e.g. 3.5 µm, 5 µm) are suitable at magnification around 20.000x.

The table below gives an overview of the available QUANTIFOIL® types with circular holes. Please be aware that the hole size and spacing might vary slightly from their nominal value, whereas the period is fix.

QUANTIFOIL® typeHole size in µmSpacing in µmPeriod in µm
R 0.6/10.61.01.6
R 1/11.01.02.0
R 1/21.02.03.0
R 1/41.04.05.0
R 1.2/1.31.21.32.5
R 1.2/201.220.021.2
R 2/12.01.03.0
R 2/22.02.04.0
R 2/42.04.06.0
R 3/33.03.06.0
R 3/53.05.08.0
R 3.5/13.51.04.5
R 5/105.010.015.0
R 5/205.020.025.0
R 6/6.56.06.512.5
R 6/1006.0100.0106.0
R 10/510.05.015.0
R 10/1010.010.020.0
R 10/2010.020.030.0
R 17/517.55.022.5